[The HLA system in the Moroccan population: General review].
Identifieur interne : 000304 ( Main/Exploration ); précédent : 000303; suivant : 000305[The HLA system in the Moroccan population: General review].
Auteurs : C. Brick [Maroc] ; O. Atouf [Maroc] ; M. Essakalli [Maroc]Source :
- Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [ 1953-8022 ]
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : HLA Antigens.
- Alleles, Anthropology, Haplotypes, Histocompatibility Antigens Class I, Humans, Morocco, Polymorphism, Genetic.
Abstract
The Moroccan population is an interesting study model of Human Leukocyte Antigen (HLA) polymorphism given its ethnic and genetic diversity. Through an analysis of the literature, this work proposes to establish a balance of knowledge for this population in the field of histocompatibility: HLA diversity, anthropology, transplantation and HLA associations and diseases. This analysis shows that the HLA system has not been fully explored within the Moroccan population. However, the results obtained allowed us to initiate a database reflecting the specific healthy Moroccan population HLA polymorphism to identify immigration flows and relationships with different people of the world and to reveal the association of certain HLA alleles with frequent pathologies. We also propose to analyze the reasons hindering the development of this activity in Morocco and we will try to identify some perspectives.
DOI: 10.1016/j.tracli.2015.10.004
PubMed: 26597780
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000512
- to stream PubMed, to step Curation: 000510
- to stream PubMed, to step Checkpoint: 000512
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- to stream Main, to step Curation: 000304
Le document en format XML
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<term>HLA Antigens (genetics)</term>
<term>Haplotypes (MeSH)</term>
<term>Histocompatibility Antigens Class I (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Morocco (MeSH)</term>
<term>Polymorphism, Genetic (MeSH)</term>
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<term>Haplotypes (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Maroc (MeSH)</term>
<term>Polymorphisme génétique (MeSH)</term>
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<front><div type="abstract" xml:lang="en">The Moroccan population is an interesting study model of Human Leukocyte Antigen (HLA) polymorphism given its ethnic and genetic diversity. Through an analysis of the literature, this work proposes to establish a balance of knowledge for this population in the field of histocompatibility: HLA diversity, anthropology, transplantation and HLA associations and diseases. This analysis shows that the HLA system has not been fully explored within the Moroccan population. However, the results obtained allowed us to initiate a database reflecting the specific healthy Moroccan population HLA polymorphism to identify immigration flows and relationships with different people of the world and to reveal the association of certain HLA alleles with frequent pathologies. We also propose to analyze the reasons hindering the development of this activity in Morocco and we will try to identify some perspectives.</div>
</front>
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